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Blood Glucose and Exercise: Signal and Response

MYP5 / IGCSE Biology

Differentiated
Difficulty

Standard mode uses checkpoints, data interpretation and short explanations.

Model

School model: adrenaline raises glucose during exercise, insulin lowers it after exercise.

Scenario

Normal response returns close to baseline in about 10 to 15 minutes.

1. Choose exercise intensity
Prediction first
Predict the pattern before you unlock the graph.

Answer the prediction to unlock Start Exercise.

2. Run the simulation
Speed
Elapsed time
0:00
Resting
Blood Glucose Concentration
Baseline about 4.8 mmol/L. Normal range shown in pale green.
Make a prediction first. Then run the model and use the graph as evidence.
LiverPancreasAdrenal
At rest
Blood glucose is close to the set point.
Make a prediction to begin.
Current blood glucose
4.80 mmol/L
Hormone levels
Adrenalinelow
Insulinnormal
At rest, hormone levels keep blood glucose close to the set point.
Mission checklist
Live checkpoint
Make a prediction first.
Data challenge
Stop exercise to unlock a calculation.
Captured readings
Before exercise-
Immediately after exercise-
10 min after stopping exercise-

Active Tasks

Use this tab to stop students just watching the line. The tasks change by difficulty.

Explanation

This keeps the assessed MYP5 idea clear, but it also gives a more accurate note for students who ask about insulin during exercise.

Assessed idea: during exercise, adrenaline is released by the adrenal glands. It signals the liver to release glucose into the blood. After exercise, insulin from the pancreas helps lower blood glucose back towards the set point by making cells take up glucose and storing excess glucose as glycogen.

1. Exercise starts

The nervous system detects activity quickly. The adrenal glands release adrenaline into the blood. Adrenaline reaches the liver and causes glycogen to break down into glucose. Blood glucose rises so working muscles have more glucose available for respiration.

2. What happens to insulin during exercise?

For this course, you can use the simple model: adrenaline raises glucose during exercise and insulin lowers it after exercise. In a more realistic model, insulin does not disappear. Some is still present, but insulin secretion is usually reduced during exercise while adrenaline and sympathetic activity are high. This helps prevent glucose being lowered too quickly while muscles need fuel.

3. Exercise stops

When exercise stops, adrenaline falls. If blood glucose is above the set point, the pancreas releases more insulin. Insulin causes body cells to take up glucose and causes the liver to store glucose as glycogen. This is negative feedback because the response reverses the rise and returns blood glucose towards normal.

Worked data example

Medium intensity starts at 4.8 mmol/L and rises to 6.5 mmol/L.

Step 1: Increase = peak value - resting value

Step 2: Increase = 6.5 - 4.8 = 1.7 mmol/L

Step 3: Blood glucose rose because adrenaline caused the liver to release glucose into the blood.

Adrenaline vs insulin

AdrenalineInsulin
Released byAdrenal glandsPancreas
Main timingDuring exercise, stress or fearWhen blood glucose is above the set point
EffectRaises blood glucoseLowers blood glucose
HowLiver releases glucose from glycogenCells take up glucose, liver stores glucose as glycogen
StageLow intensityMedium intensityHigh intensity
Before exercise---
Immediately after exercise---
10 min after stopping exercise---

Analysis prompts

1. Describe the pattern using numbers.

2. Explain the rise using adrenaline, liver, glycogen and glucose.

3. Explain the fall using insulin, pancreas, cells and negative feedback.

4. Compare this model to your heart rate practical. Why are both useful during exercise?

5. Challenge: identify one limitation of this model.

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